Isolation, Primary Structure, and Effects on -Melanocyte-Stimulating Hormone Release of Frog Neurotensin
نویسندگان
چکیده
منابع مشابه
Isolation of melanocyte-stimulating hormone from hog pituitary gland.
The present communication is concerned with two substances possessing melanocyte-stimulating hormone (MSH) activity, ar-MSH and /3-MSH, found in hog pituitary gland. The main component, o(-MSH, was isolated by a four-step process consisting of solvent extraction and fractional precipitation, oxycellulose adsorption, counter-current distribution, and paper electrophoresis. a-MSH has been found t...
متن کاملY2-Melanocyte-Stimulating Hormone
Peptides of the pro-opiocortin class produce pronounced cardiovascular and natriuretic actions. We have investigated the acute cardiovascular effects of one of the most potent members of this class, y2-melanocyte stimulating hormone (y2-MSH), in rats. Pressor actions of y2MSH administered systemicaMy were eliminated by ganglionic blockade with chlorisondamine. Peripheral cholinergic blockade fa...
متن کاملIsolation of tyrosine-melanocyte-stimulating hormone release-inhibiting factor 1 from bovine brain tissue.
Although Tyr-melanocyte-stimulating hormone release-inhibiting factor 1 (MIF-1) (Tyr-Pro-Leu-Gly-NH2) can exert a number of biological actions in the brain and elsewhere, it has never been isolated from any tissue. Accordingly, we attempted to purify it from acetic acid extracts of bovine brain tissue by gel filtration chromatography and several different high performance liquid chromatographic...
متن کاملRegulation of formation and proposed structure of the factor inhibiting the release of melanocyte-stimulating hormone.
Microsomal preparations from the stalk median eminence of female rats are shown to contain an enzymic activity that is responsible for the formation of MSH-release-inhibiting factor (MSH-R-IF). The amount of this activity remains constant throughout the estrous cycle. The corresponding mitochondrial preparations from the stalk median eminence contain another enzymic principle, estrous cycle-dep...
متن کاملDesacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance
OBJECTIVE Regulation of energy balance depends on pro-opiomelanocortin (POMC)-derived peptides and melanocortin-4 receptor (MC4R). Alpha-melanocyte stimulating hormone (α-MSH) is the predicted natural POMC-derived peptide that regulates energy balance. Desacetyl-α-MSH, the precursor for α-MSH, is present in brain and blood. Desacetyl-α-MSH is considered to be unimportant for regulating energy b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrinology
سال: 1998
ISSN: 0013-7227
DOI: 10.1210/en.139.10.4140